The medical black technology system of the top student

Lu Liang opened his system, and the panel appeared in front of Lu Liang. He opened the task interface skillfully.

Temporary tasks also popped up very consciously.

[Task: Clobazam imitation (completed)]

[Time taken: 12 days. 】

[Task Rating: A]

[Task rewards have been distributed. 】

The production of clobazam took a total of twelve days.

When he saw this score, Lu Liang was somewhat surprised.

After all, it only took him five days to complete the last temporary task, and the system gave him an A-level rating.

But this time it took him twelve days, and the system still gave him an A grade.

He originally thought that after such a long delay this time, he might only get a B-level rating.

Does it mean that if you complete it within the specified time, you will get an A grade?

After Lu Liang thought about it, it seemed that this was the only explanation.

But then again, during these twelve days, Wang Wentao was actually the hardest working person.

After all, every time Lu Liang proposed a new idea, Wang Wentao had to spend a whole day busy in the laboratory.

Thinking of this, Lu Liang looked at Wang Wentao. At this moment, Wang Wentao was eating his meal with a satisfied look on his face, and seemed to have no complaints about his previous work.

A bucket of fried chicken will solve the problem. Why is this kid so easy to get rid of?

Lu Liang shook his head and thought.

Afterwards, Lu Liang once again focused on the reward.

Just like the last temporary mission, he noticed a semi-illusory light group appearing in front of his eyes.

However, it was also rated A-level. Last time it was a golden light group, but this time it was a silver-gray light group.

Lu Liang suddenly slapped his thigh in annoyance. He should have washed his face before accepting the award.

Forget it, let's just say silver gray. It's an A-grade rating anyway, no matter how bad it is, it can't be much worse, Lu Liangliang thought.

Then, Lu Liang took a look at the contents of the eyeball.

However, when Lu Liang saw what was inside the light ball, he was stunned for a moment.

The shape of the thing is very strange, like the structure of some kind of protein.

Could this be a reward for research on protein conformation and function?

Lu Liang's face suddenly turned black.

If it was what he guessed, then this reward wouldn't mean much to him.

After hesitating for a moment, Lu Liang chose to put his hand into the ball of light.

In an instant, Lu Liang felt a large amount of information pouring into his mind.

It consists of 163 amino acids, has a relative molecular mass of 18,000, and contains 2 structural domains.

The N-terminal tryptophan-tryptophan central domain consists of 1 to 39 amino acids and is involved in recognizing and binding the pSer/Thr-Pro motif of the substrate.

The C-terminal catalytic domain consists of 45 to 163 amino acids, with isomeric pSer/Thr-Pro amide bonds, inducing conformational changes in the protein.

Is this isomerase?

The moment he received the information, such a term appeared in Lu Liang's mind.

The so-called isomerase is the general name for enzymes that catalyze the reaction to generate isomers. It is one of the main categories in enzyme classification.

Its main function is the redox reaction within the molecule, such as the glucose phosphate isomerase that generates fructose phosphate, or the transfer reaction of groups within the molecule.

Judging from the received information, the system rewards itself with the physical and chemical properties and biological information of a peptidyl prolyl isomerase Pin1.

Speaking of Pin1, we have to mention phosphorylation modification.

As everyone knows.

The phosphorylation modification of serine or threonine before proline in proteins plays an important role in the life process of cells and participates in the regulation of various cell signal transduction pathways.

Pin1 is an isomerase with phosphorylation modification.

Pin1 specifically recognizes the phosphorylated serine/threonine-proline motif in protein molecules.

Then it catalyzes the change of its peptide bond configuration, affecting the function of the phosphorylated protein.

Pin1 mainly has three functions: transcriptional regulation, phosphorylation modification and oxidative modification, which can change the conformation of the protein and affect its activity and stability.

Lu Liang knows all these.

But the question is, if the system gives itself the physical and chemical properties and biological information of such an isomerase, what does it want it to do?

Are you implying that you are too good at it and should change your career quickly and change your major?

Lu Liang was a little confused for a while, but he continued to digest the information with questions.

However, when Lu Liang digested the subsequent key information.

"Hold the grass!"

Lu Liang suddenly opened his eyes, with a look of astonishment on his face, and the essence of the Chinese nation blurted out subconsciously.

The reward given to him by the system is a brand new cancer target!

This is the peptidyl prolyl isomerase Pin1, which does not seem to have much to do with cancer.

Turns out to be a brand new cancer target? !

As we all know, the best way to deal with monsters like cancer is to find the key targets.

For cancer, the target is like the tubes of a person's lungs.

Containing the target is like pinching a person's lung tube.

Generally speaking, the targets of cancer are certain key molecules or signaling pathways.

But Lu Liang never expected that one day, isomerase would also become a target.

It took Lu Haohao a while to recover from the shock.

His eyes once again returned to the peptidyl prolyl isomerase Pin1.

Judging from the existing research.

If there is a relationship between Pin1 and cancer, then there is indeed a slight relationship.

But to say it has a big relationship, it’s not that big.

First, Pin1 is linked to cancer, mainly because of the tumor suppressor gene p35.

Many studies have shown that Pin1 plays a crucial role in maintaining the integrity of the tumor suppressor gene p53.

Loss of function of the tumor suppressor gene p35 has been found in many cancer patients.

The tumor suppressor gene p53 is a substrate of Pin1. When DNA is damaged, Pin1 can mediate the accumulation and function of the tumor suppressor gene p53, making the tumor suppressor gene p35 more stable and activated.

But the problem is that these studies can only show that there is an indirect relationship between Pin1 and cancer, and there is no direct connection.

Lu Liang thought for a moment, then opened a new word on his computer and created a trial plan in word.

This time, the reward the system provided him was a specific target.

But the problem is, Lu Liang doesn't know exactly how this target works.

This is equivalent to pointing out a direction for Lu Liang.

Therefore, he must only judge through the experimental results what role Pin1 can play in cancer.

When Lu Liang was writing the first sentence of the test plan, Lu Liang's fingers tapping on the computer suddenly paused.

By the way, which cancer target is Pin1?

The targets of each cancer are different.

Lu Liang closed his eyes and began to recall carefully.

However, when Lu Liang recalled which type of cancer Pin1 was targeting, a look of astonishment once again appeared on Lu Liang's face.